December 30, 2021 Pueblo, CO – Today, Pueblo Department of Public Health and Environment (PDPHE) updated its guidance regarding COVID-19 isolation and quarantine by vaccination status for the general population to align with the Colorado Department of Public Health and Environment (CDPHE). This updated guidance does not apply to schools and congregate settings, as local public health is waiting for revised guidance from the Centers for Disease Control and Prevention (CDC) for these select categories, expected next week. 


Pueblo’s current updated isolation and quarantine guidance by vaccination status contains the following changes, please note this guidance is subject to future change: 

  • Increased to three categories by vaccination status, before only two. The three categories are: Unvaccinated or Partially Vaccinated, Fully Vaccinated > 6 months mRNA or 2 months J&J without Booster or Recently Fully Vaccinated < 6 months mRNA or 2 months J&J or Received Booster 
  • Individuals who test positive or are awaiting test results, isolate regardless of vaccination status for 5 days at home. If remaining asymptomatic or symptoms improve the individual can leave isolation on day 6. The last 5 days they must wear a mask and continue to symptom monitor. 
  • Individuals exposed to COVID-19 quarantine for 5 days based on vaccination status. On day 5 if individuals remain asymptomatic they must test and receive a negative test result to leave quarantine on day 6-14. Individuals must wear a mask and continue to conduct daily symptom monitoring through day 14. 


PDPHE continues to recommend prevention and treatment strategies to reduce the spread of COVID-19 and help protect against severe illness: 

  • Get vaccinated against COVID-19 and get your booster if you are eligible 
    To get information on where you can get vaccinated visit 

  • Get tested: individuals who feel sick or are experiencing symptoms of COVID-19 should seek testing and follow the isolation recommendations in Pueblo’s updated guidance. 
    To get more information on where to get tested, visit  

  • If you have tested positive for COVID-19, consult with your doctor or health care provider to see if you are a good candidate for COVID-19 therapeutics. 

  • Stay home when sick 

  • Where a face covering in public indoor settings, regardless of vaccination status.